... cont: but if cellular signalling events are like parties, then maybe one could use parties to describe and learn about signalling events. Choose the right descriptors, record party, match party descriptors to characteristics of known signalling events, identify best matching signalling event, and then use party dynamics to learn about best matching signalling event (complete, extrapolate, test hypothesis). "After the third drink, Sue sat on the couch to chill; this attracted quickly Pete, Jo and Matt. Sue would have preferred to chat with the cute Ben, but he was off wiggling his bum to impress Amy. But Pete was quite funny tonight, so she sat down for a while and listened; Matt thought some more drinks might help getting things going, and went off to fetch some from the fridge. This however perturbed the starting love affair between Jean and Nelly; Nelly had to leave just thereafter, and went to Singapore next day without exchanging email addresses with Jean. As a result they did not get married, her son Kevin was not born and
could not save London from a fatal bio-gas attack forty years later." Maybe this matches to T cell receptor signalling? I guess we will learn to appreciate the importance of the unspectacular parties, and signalling events, to keep up criticallity.
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